Co-codamol 8/500


Co-codamol 8/500 is a combination pain relief medication containing two active ingredients: 8 mg of codeine phosphate and 500 mg of paracetamol (acetaminophen).

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What is Co-codamol 8/500?

This medication is used to treat moderate pain that is not relieved by paracetamol alone. Codeine is an opioid pain reliever that works by blocking pain signals in the brain, while paracetamol reduces the production of prostaglandins, chemicals in the body that cause pain and inflammation. Together, these ingredients provide a synergistic effect that enhances pain relief.


Before taking Co-codamol 8/500, it is important to inform your healthcare provider about any medical conditions or allergies, especially those related to the liver, kidneys, respiratory system, or gastrointestinal tract. Patients with a history of substance use disorder, mental health issues, or chronic alcohol use should use Co-codamol with caution, as codeine can be habit-forming. Additionally, combining this medication with other central nervous system depressants, such as alcohol, sedatives, or certain antidepressants, can increase the risk of severe side effects like respiratory depression. It is crucial to follow the prescribed dosage and not to exceed the recommended amount, as an overdose of paracetamol can cause serious liver damage.


Co-codamol 8/500 is beneficial for individuals experiencing moderate pain that cannot be controlled by paracetamol alone. The combination of codeine and paracetamol offers effective relief for conditions such as headaches, migraines, dental pain, muscular pain, and arthritis. By providing dual mechanisms of action—central and peripheral pain relief—Co-codamol can enhance the overall effectiveness of pain management, improve comfort, and enhance the quality of life for those with persistent pain conditions.

Side Effects

Common side effects of Co-codamol 8/500 include nausea, vomiting, constipation, dizziness, and drowsiness. These side effects are generally mild and tend to decrease as the body adapts to the medication. However, more serious side effects can occur, such as severe allergic reactions, difficulty breathing, or significant mood changes. Long-term use or misuse of Co-codamol can lead to dependence and tolerance, requiring higher doses to achieve the same pain relief effect. Sudden discontinuation after prolonged use may result in withdrawal symptoms. It is essential to use this medication under the guidance of a healthcare provider and report any unusual or severe side effects promptly.


Proper storage of Co-codamol 8/500 is necessary to maintain its effectiveness and prevent misuse. The medication should be stored in a tightly closed container at room temperature, away from moisture, heat, and direct light. Keep it out of reach of children and pets. Unused or expired Co-codamol should be disposed of safely, preferably through a medication take-back program or by following specific disposal instructions provided by a pharmacist or local waste disposal company. Flushing the medication down the toilet or throwing it in the trash is not recommended due to environmental risks and potential misuse by others.


Co-codamol 8/500 is a powerful combination medication for managing moderate pain that is unresponsive to paracetamol alone. Its dual-action approach provides significant pain relief and can improve the quality of life for those with persistent pain conditions. However, due to the risk of side effects, dependence, and interactions with other substances, it is crucial to use Co-codamol under strict medical supervision. By following medical advice, taking necessary precautions, and properly storing the medication, patients can safely and effectively use Co-codamol to manage their pain.


Additional information


50 Tablets, 100 Tablets


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